منابع مشابه
Centrosomes take sides
endritic cells present antigens during immune responses and are thought to be important in antitumor activity. However, under the influence of the known cancer promoter VEGF-A, dendritic cell precursors take on the trappings of endothelial cells and contribute to tumor blood vessels, speeding the cancer’s growth, according to a report by Jose Conejo-Garcia, Fabian Benencia, George Coukos (Unive...
متن کاملThou Shalt Not Take Sides: Cognition, Logic and the Need for Changing How We Believe
We believe in many different ways. One very common one is by supporting ideas we like. We label them correct and we act to dismiss doubts about them. We take sides about ideas and theories as if that was the right thing to do. And yet, from a rational point of view, this type of support and belief is not justifiable. The best we can hope when describing the real world, as far as we know today, ...
متن کاملCentrosomes and tumour suppressors.
Centrosomes are microtubule organising centres that act as spindle poles during mitosis. Recent work implicates centrosomes in many other processes, and shows that centrosome defects can cause genetic instability. Many regulators of mammalian centrosome function were predicted from studies of model systems. Surprisingly, some well-known tumour suppressors have recently been found at centrosomes...
متن کاملCentrosomes: Methods for Preparation
The centrosome of higher eukaryotic cells is the main microtubule-organising centre. To understand the molecular mechanisms underlying this organelle’s biogenesis and important functions in several cellular processes, such as microtubule nucleation, cell division and stress response, it was critical to develop methods for isolating biochemically meaningful quantities of centrosomes. Centrosomes...
متن کاملCentrosomes: Central no more?
It has recently been found that the zygotic development of a morphologically normal fly can occur without properly functioning mitotic centrosomes. Does this mean that centrosomes are not required for cell division in animals at all?
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2004
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1667rr2